The GenTAC Alliance is a community of stakeholders committed to advancing our understanding of genetically induced thoracic aortic diseases and their treatment. The GenTAC Alliance was initiated in 2017 to harness the synergy and collaborations created by the GenTAC Registry (the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Related Cardiovascular Conditions), which was funded by NHLBI and NIAMS, and enrolled and followed over 3600 patients from 2006 through 2016.
The goal of the GenTAC Alliance is to continue to harness the synergy driven by the GenTAC Registry, in maintaining and enhancing collaboration of stakeholders to advance scientific discovery and clinical practice, and address patient and provider education needs, with regard to genetically-triggered thoracic aortic disease and related cardiac and non-cardiac complications. It is the intent for the GenTAC Alliance to encompass a much wider group of stakeholders than the previous GenTAC Registry, open to any type of stakeholder with an interest in thoracic aortic conditions, including but not limited to researchers, patients, family members of patients, patient advocacy groups, clinicians, academic institutions, professional societies, and industry organizations. It is anticipated and hoped that the GenTAC Alliance will leverage the resources created through the initial GenTAC Registry, as well as other existing and new registries, to facilitate stakeholder collaboration on publications, foster new research collaborations, and identify and tap new resources to support grant opportunities for thoracic aortic disease.
Goals of the GenTAC Alliance include:
Enhancing the scope of research and expanding collaborations to improve clinical management of genetically induced thoracic aortic diseases.
Facilitating effective coordination of the scientific efforts among stakeholders. Addressing unique educational needs of providers, patients and families with or at risk for genetically induced thoracic aortic diseases.
Enlarging the partnerships to include other related registries, professional organizations and industry partners whose missions include improving the diagnosis and treatment of genetically induced thoracic aortic diseases.
Promoting use and sharing of the resources (data, specimens and images) created by GenTAC and related registries to enable and foster new research collaborations and publications.
Identifying and tapping new resources to support grant opportunities for research on genetically induced thoracic aortic diseases.
GenTAC Alliance Organizational Chart
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Learn about working group mandates and the work group members.
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